Advancing Atopic Dermatitis Research at NellaDerm
At NellaDerm, we are dedicated to transforming the way atopic dermatitis is managed through cutting-edge, safe, and effective solutions grounded in science and technology. Founded on a commitment to evidence-based innovation, our mission is to develop steroid-free therapies that support long-term skin healing without compromising safety, especially for individuals suffering from chronic, relapsing skin inflammation.
Our research efforts span formulation science, dermal delivery systems, and AI-assisted personalized management tools, positioning NellaDerm as a unique bridge between AI, biomedical research, and next-generation dermatology technologies.
A New Paradigm in AD Care
Topical corticosteroids remain the most commonly prescribed treatment for eczema, but long-term use is associated with adverse effects, including skin thinning, rebound flare-ups, and systemic absorption risks, especially in children.
At NellaDerm, we are developing a new class of non-steroidal topical formulations that focus on barrier restoration, inflammation modulation, and flare prevention. Our product development is grounded in:
Bioactive compounds with clinically supported anti-inflammatory and skin-calming effects.
Advanced excipient technologies that ensure stability, penetration, and user compliance.
Skin barrier science, incorporating moisturizers and lipid-replenishing systems.
Products
Our initial products, now available under the NellaDerm brand for mild to moderate atopic dermatitis, have received overwhelmingly positive feedback from early users and health professionals, noting their soothing effect, rapid itch relief, and gentle action on sensitive skin.

Our R&D Research
– Delivery systems
One of our core research focus areas is the development of advanced delivery systems that can target active ingredients deep into the skin layers, ensuring high efficacy with minimal irritation.
Led by Dr. Janfaza, our scientific team is exploring multiple dermal delivery platforms, including:
Nanoparticle-based systems
Hydrogel and liposomal carriers to enhance penetration and release profiles.
Bioadhesive delivery matrices for extended skin contact.
These technologies aim to overcome the limitations of conventional creams and ointments, ensuring the actives reach the stratum corneum and beyond, where eczema-related inflammation and barrier dysfunction originate.

– AI-Powered Personalized Atopic Dermatitis Management
In parallel with our topical research, NellaDerm is also working on the development of a first-of-its-kind AI-powered platform for eczema care, designed to:
Track triggers (diet, stress, weather, allergens) through smart data integration.
Personalize treatment recommendations based on user symptoms, history, and skin response.
Predict flare-ups using real-time analysis and machine learning models.
This platform will empower both patients and dermatologists by offering decision support tools tailored to each individual’s journey. We aim to move beyond one-size-fits-all care by incorporating data-driven personalization into eczema treatment and prevention.
Learn more at: www.myeczema.app
Start Your Journey to Better Atopic Dermatitis Management
Get early access to our AI-powered platform that helps predict flare-ups, identify triggers, and provides personalized guidance for your Atopic Dermatitis journey.
Personalized Insights
AI-driven recommendations based on your unique triggers and patterns
Early Detection
Predict flare-ups before they happen with our advanced algorithms
Trigger Analysis
Identify and understand your specific Atopic Dermatitis triggers
24/7 AI Coach
Get instant guidance and support whenever you need it
Trusted by dermatologists and researchers worldwide
In Collaboration With
Partnering with world-leading institutions to advance eczema research
Harvard University
Department of Dermatology research collaboration and clinical validation studies
Stanford University
AI and machine learning research partnership for predictive analytics
University of British Columbia
Clinical research and patient outcome studies in dermatology
Research & Development
Evidence-Based Approach
All features are developed based on peer-reviewed research and clinical studies
Continuous Innovation
Ongoing research partnerships ensure our technology stays at the forefront of dermatology
Patient-Centered Design
Every feature is developed with direct input from eczema patients and dermatologists
Backed by World-Class Technical Excellence
Our platform is built and continuously improved by a dedicated team of AI specialists, dermatology experts, and software engineers committed to transforming eczema care through technology.
AI & Machine Learning
Advanced algorithms trained on thousands of eczema cases for accurate predictions and personalized insights
Medical Expertise
Guidance from dermatology specialists ensuring all recommendations are clinically sound and evidence-based
Software Engineering
Robust, secure, and scalable infrastructure ensuring reliable performance and data protection
Research, Publications, and Patents
Our team has an established track record in biomedical engineering, drug delivery, and skin barrier research, with a portfolio of peer-reviewed publications, conference presentations, and patent filings in these fields.
Our scientific team has published extensively on topics such as biomaterials for dermatological applications, transdermal drug delivery, and inflammation modulation.
Selected Publications:
– Janfaza et al. Next-Generation Atopic Dermatitis Treatments Based on Nanotechnology as an Effective and Low-Side-Effect Solution, Oxford Material Science, 2025
-Janfaza, S., & Razavi, S., Lipid-based nanoformulations for treatment of skin diseases. Nanotechnology Applied to Pharmaceutical Technology (pp. 247–266).
🔍 NellaDerm Innovation + delivery system


Collaborations & Clinical Validation
At NellaDerm, we believe that meaningful innovation happens through interdisciplinary and clinical collaboration. Our research is strengthened by partnerships with:
Clinical dermatology practices and skin research clinics for patient feedback and evaluation.
Academic institutions across British Columbia for preclinical testing and AI model development.
Accelerators and support
networks including:Innovation UBC
SFU VentureLabs
Natural Products Canada (NPC)
CHFA Incubator Alley
Our Academic Collaborators:
Global Leaders in Atopic Dermatitis Research
National Institute of Allergy and Infectious Diseases (NIAID)
Pioneering microbiome research with topical probiotics (R. mucosa) and epithelial barrier studies
Visit Research PortalUC San Diego Dermatology Research
Leading clinical trials on microbiome-targeted therapies (S. hominis A9) and longitudinal transcriptomic analysis
View Clinical TrialsNIAMS Dermatology Branch
Researching skin barrier dysfunction, itch neurobiology, and microbiome-immune interactions
Explore ResearchInternational Society of Atopic Dermatitis
Global research network coordinating Georg RAJKA symposia and fellowship programs
Access Society ResourcesSanofi & Regeneron
Clinical research on Dupixent® in diverse populations and DISCOVER studies for skin of color
Read DISCOVER StudyTFS HealthScience Dermatology CRO
Specialized contract research organization advancing eczema clinical trials globally
Learn About TrialsNellaDerm
If you’re interested in collaborating, have questions, or want to learn more about our research, we’d love to hear from you.
Reach out to us at: admin@nelladerm.com


