Advancing Atopic Dermatitis Research at NellaDerm

At NellaDerm, we are dedicated to transforming the way atopic dermatitis is managed through cutting-edge, safe, and effective solutions grounded in science and technology. Founded on a commitment to evidence-based innovation, our mission is to develop steroid-free therapies that support long-term skin healing without compromising safety, especially for individuals suffering from chronic, relapsing skin inflammation.

Our research efforts span formulation science, dermal delivery systems, and AI-assisted personalized management tools, positioning NellaDerm as a unique bridge between AI, biomedical research, and next-generation dermatology technologies.

 

A New Paradigm in AD Care

Topical corticosteroids remain the most commonly prescribed treatment for eczema, but long-term use is associated with adverse effects, including skin thinning, rebound flare-ups, and systemic absorption risks, especially in children.

At NellaDerm, we are developing a new class of non-steroidal topical formulations that focus on barrier restoration, inflammation modulation, and flare prevention. Our product development is grounded in:

  • Bioactive compounds with clinically supported anti-inflammatory and skin-calming effects.

  • Advanced excipient technologies that ensure stability, penetration, and user compliance.

  • Skin barrier science, incorporating moisturizers and lipid-replenishing systems. 

Products

Our initial products, now available under the NellaDerm brand for mild to moderate atopic dermatitis, have received overwhelmingly positive feedback from early users and health professionals, noting their soothing effect, rapid itch relief, and gentle action on sensitive skin.

Eczema products

Our R&D Research

– Delivery systems

One of our core research focus areas is the development of advanced delivery systems that can target active ingredients deep into the skin layers, ensuring high efficacy with minimal irritation.

Led by Dr. Janfaza, our scientific team is exploring multiple dermal delivery platforms, including:

  • Nanoparticle-based systems 

  • Hydrogel and liposomal carriers to enhance penetration and release profiles.

  • Bioadhesive delivery matrices for extended skin contact.

These technologies aim to overcome the limitations of conventional creams and ointments, ensuring the actives reach the stratum corneum and beyond, where eczema-related inflammation and barrier dysfunction originate.

Eczema treatment technology UBC

 

– AI-Powered Personalized Atopic Dermatitis Management

In parallel with our topical research, NellaDerm is also working on the development of a first-of-its-kind AI-powered platform for eczema care, designed to:

  • Track triggers (diet, stress, weather, allergens) through smart data integration.

  • Personalize treatment recommendations based on user symptoms, history, and skin response.

  • Predict flare-ups using real-time analysis and machine learning models.

This platform will empower both patients and dermatologists by offering decision support tools tailored to each individual’s journey. We aim to move beyond one-size-fits-all care by incorporating data-driven personalization into eczema treatment and prevention.

Learn more at: www.myeczema.app

 

In Collaboration With

Partnering with world-leading institutions to advance eczema research

Harvard University

Department of Dermatology research collaboration and clinical validation studies

Stanford University

AI and machine learning research partnership for predictive analytics

University of British Columbia

Clinical research and patient outcome studies in dermatology

Research & Development

Evidence-Based Approach

All features are developed based on peer-reviewed research and clinical studies

Continuous Innovation

Ongoing research partnerships ensure our technology stays at the forefront of dermatology

Patient-Centered Design

Every feature is developed with direct input from eczema patients and dermatologists

Expert Team

Backed by World-Class Technical Excellence

Our platform is built and continuously improved by a dedicated team of AI specialists, dermatology experts, and software engineers committed to transforming eczema care through technology.

AI & Machine Learning

Advanced algorithms trained on thousands of eczema cases for accurate predictions and personalized insights

Medical Expertise

Guidance from dermatology specialists ensuring all recommendations are clinically sound and evidence-based

Software Engineering

Robust, secure, and scalable infrastructure ensuring reliable performance and data protection

15+
Years Combined Experience
PhD
Advanced Degrees
100k+
Lines of Code
Meet Our Team
Industry Veterans
Award-Winning

Research, Publications, and Patents

Our team has an established track record in biomedical engineering, drug delivery, and skin barrier research, with a portfolio of peer-reviewed publications, conference presentations, and patent filings in these fields.

Our scientific team has published extensively on topics such as biomaterials for dermatological applications, transdermal drug delivery, and inflammation modulation.

Selected Publications:

– Janfaza et al. Next-Generation Atopic Dermatitis Treatments Based on Nanotechnology as an Effective and Low-Side-Effect Solution, Oxford Material Science, 2025 

-Janfaza, S., & Razavi, S., Lipid-based nanoformulations for treatment of skin diseases. Nanotechnology Applied to Pharmaceutical Technology (pp. 247–266).



🔍  NellaDerm Innovation + delivery system 

NellaDerm atopic dermatitis, Eczema research

Collaborations & Clinical Validation

At NellaDerm, we believe that meaningful innovation happens through interdisciplinary and clinical collaboration. Our research is strengthened by partnerships with:

  • Clinical dermatology practices and skin research clinics for patient feedback and evaluation.

  • Academic institutions across British Columbia for preclinical testing and AI model development.

  • Accelerators and support networks including:

    • Innovation UBC

    • SFU VentureLabs

    • Natural Products Canada (NPC)

    • CHFA Incubator Alley

Our Academic Collaborators:

UBC, Stanford University, NellaDerm

Atopic Dermatitis Research Partners | NellaDerm

Global Leaders in Atopic Dermatitis Research

National Institute of Allergy and Infectious Diseases (NIAID)

Pioneering microbiome research with topical probiotics (R. mucosa) and epithelial barrier studies

Visit Research Portal

UC San Diego Dermatology Research

Leading clinical trials on microbiome-targeted therapies (S. hominis A9) and longitudinal transcriptomic analysis

View Clinical Trials

NIAMS Dermatology Branch

Researching skin barrier dysfunction, itch neurobiology, and microbiome-immune interactions

Explore Research

International Society of Atopic Dermatitis

Global research network coordinating Georg RAJKA symposia and fellowship programs

Access Society Resources

Sanofi & Regeneron

Clinical research on Dupixent® in diverse populations and DISCOVER studies for skin of color

Read DISCOVER Study

TFS HealthScience Dermatology CRO

Specialized contract research organization advancing eczema clinical trials globally

Learn About Trials

NellaDerm

If you’re interested in collaborating, have questions, or want to learn more about our research, we’d love to hear from you.

Reach out to us at: admin@nelladerm.com

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