Best Moisturizers for Eczema & Dry Skin: Dermatologist-Trusted Soothing Cream for Adults

If you’re struggling with itchy, flaky, or inflamed skin, you’re not alone—eczema affects nearly 1 in 10 adults in Canada alone, according to the Canadian Dermatology Association. And while topical steroids and other treatments have their place, one step remains non-negotiable in any regimen: moisturizing. Choosing the best moisturizers for eczema isn’t just about comfort—it’s central to restoring your skin’s barrier and preventing flare-ups.

This blog breaks down how to select the most effective moisturizer, when to apply it, and what ingredients to look for based on dermatological evidence. 

Why Moisturizing Matters in Eczema Care

Eczema-prone skin lacks the natural lipids and proteins that form a healthy skin barrier. That means it loses moisture easily and allows irritants in—creating the infamous itch-scratch-flare cycle.

A proper moisturizer acts as an external barrier, sealing in hydration and reducing exposure to environmental triggers. Daily use can:

• Reduce itchiness and redness
• Decrease reliance on steroids
• Prolong periods between flare-ups
• Improve quality of life

Evidence: In a landmark study published in JAMA Dermatology, regular use of emollients reduced eczema incidence by over 50% in high-risk patients [Simpson et al., 2014]

Understanding Moisturizer Types: Creams vs. Lotions vs. Ointments

Different textures suit different needs. Here’s a quick comparison:

For eczema, creams or ointments are preferred. Lotions contain more water and evaporate quickly—offering little benefit to compromised skin.

Key Ingredients in the Best Moisturizers for Eczema

1. Ceramides

Ceramides are lipids found naturally in the skin. They form the “mortar” between skin cells. Eczema-prone skin is often deficient in ceramides, which leads to barrier dysfunction.

Why it works: Replenishing ceramides restores barrier integrity and retains moisture.

Evidence: Studies show ceramide-based moisturizers improve eczema severity scores and reduce the need for topical steroids [Proksch et al., 2014].

2. Humectants: Glycerin, Urea, and Hyaluronic Acid

Humectants attract and bind water to the skin.

• Glycerin helps draw moisture from the air.
• Urea improves hydration and gently exfoliates dead skin (in concentrations under 10%).
• Hyaluronic acid boosts skin elasticity and hydration.

Caution: In dry climates, always apply humectants under an occlusive layer (like petrolatum or shea butter) to prevent moisture being pulled out of the skin.

3. Occlusives: Petrolatum, Shea Butter, Dimethicone

Occlusives prevent water loss by forming a protective barrier over the skin.

• Petrolatum (like in Vaseline) is highly effective, though greasy
• Dimethicone is lightweight and found in many eczema creams
• Shea butter provides a natural, soothing seal

4. Anti-inflammatory Additives: Niacinamide and Colloidal Oatmeal

• Niacinamide (Vitamin B3) reduces redness and inflammation while improving barrier repair.
• Colloidal oatmeal is a Health Canada–approved skin protectant with anti-itch and soothing properties.

Evidence: A 2020 double-blind study confirmed colloidal oatmeal’s effectiveness in reducing itch and skin scaling in atopic patients [JDD, 2020].

What to Avoid in a Moisturizer for Eczema

The best moisturizers for eczema are free from:

• Fragrances and dyes
• Alcohol or menthol
• Harsh preservatives like methylisothiazolinone (MI)
• Essential oils or botanical extracts 
• Note: Even “natural” products can cause irritation. Always patch-test new products before applying widely.

When and How to Apply Moisturizer

Timing is everything.

Rule of 3 Minutes: Apply moisturizer within three minutes of bathing to lock in hydration (“soak and seal” method).

Frequency:

• 2x daily for maintenance
• More during winter or after sweating
• Immediately after hand washing or exposure to water

Technique:

• Use clean, dry hands
• Apply in downward strokes (don’t rub vigorously)
• Cover all affected and dry areas—even those that “look fine”

Product & Lifestyle Integration: Building an Effective Routine

An ideal routine for adults with eczema includes:

Morning:

• Gentle, fragrance-free cleanser
• Moisturizer with ceramides + niacinamide
• SPF 30+ if going outdoors

Evening:

• Cleanse face/body with lukewarm water
• Moisturizer or ointment (can layer balm on top if needed)
• Apply prescription cream to active flare spots first

Try NellaDerm’s moisturising cream – developed with dermatologists for deep hydration without steroids.

Read the Cleveland Clinic’s guide to eczema moisturizers for expert comparisons and ingredient advice.

Closing Takeaways

Choosing the best moisturizer for eczema is one of the most important decisions in your skincare routine. Look for ceramide-rich creams with added humectants and occlusives, while avoiding irritants like fragrances and alcohol. Apply at least twice daily—and especially after bathing—to maintain hydration and reduce flare-ups.

Remember, consistency is key. With the right moisturizer, eczema-prone adults can enjoy smoother, calmer skin—and maybe even fewer visits to the dermatologist.